Jonathan, E2008-07-292008-07-292008-01Jonathan, E. 2007. In vivo sweat film layer thickness measured with Fourier-domain optical coherence tomography. Optics and Lasers in Engineering, Vol. 46(6), pp 424-4270143-8166http://www.science-direct.com/science?_ob=MImg&_imagekey=B6V4G-4S08YKN-1-7&_cdi=5758&_user=958262&_orig=browse&_coverDate=06%2F30%2F2008&_sk=999539993&view=c&wchp=dGLbVzz-zSkWA&md5=ec30c835de9288128e843c65a4fffe15&ie=/sdarticle.pdfhttp://hdl.handle.net/10204/2336Copyright: 2008 Elsevier Ltd All rights reservedWhile human sweat secretion is accepted as a mechanism by which the body cools off, excessive sweating (hyperhidrosis) is now appreciated as a medical condition and the primary site for diagnosis is the palm of the hand. We propose sweat film layer thickness as a potential clinical diagnostic parameter when screening for excessive sweating. In this preliminary study we demonstrate the usefulness of Fourier-domain optical coherence tomography (FD-OCT) for measurement of sweat film thickness in vivo with micron-scale resolution on the hand of a human volunteer. FD-OCT has a superior image acquisition time and identification of active sweat glands, ducts and pores is also possible.enIn vivo sweat film layer thicknessFourier-domain optical coherence tomography(FD-OCT)Human sweat secretionSweat glandSweat ductHyperhidrosisArticleJonathan, E. (2008). In vivo sweat film layer thickness measured with Fourier-domain optical coherence tomography. http://hdl.handle.net/10204/2336Jonathan, E "In vivo sweat film layer thickness measured with Fourier-domain optical coherence tomography." (2008) http://hdl.handle.net/10204/2336Jonathan E. In vivo sweat film layer thickness measured with Fourier-domain optical coherence tomography. 2008; http://hdl.handle.net/10204/2336.TY - Article AU - Jonathan, E AB - While human sweat secretion is accepted as a mechanism by which the body cools off, excessive sweating (hyperhidrosis) is now appreciated as a medical condition and the primary site for diagnosis is the palm of the hand. We propose sweat film layer thickness as a potential clinical diagnostic parameter when screening for excessive sweating. In this preliminary study we demonstrate the usefulness of Fourier-domain optical coherence tomography (FD-OCT) for measurement of sweat film thickness in vivo with micron-scale resolution on the hand of a human volunteer. FD-OCT has a superior image acquisition time and identification of active sweat glands, ducts and pores is also possible. DA - 2008-01 DB - ResearchSpace DP - CSIR KW - In vivo sweat film layer thickness KW - Fourier-domain optical coherence tomography KW - (FD-OCT) KW - Human sweat secretion KW - Sweat gland KW - Sweat duct KW - Hyperhidrosis LK - https://researchspace.csir.co.za PY - 2008 SM - 0143-8166 T1 - In vivo sweat film layer thickness measured with Fourier-domain optical coherence tomography TI - In vivo sweat film layer thickness measured with Fourier-domain optical coherence tomography UR - http://hdl.handle.net/10204/2336 ER -