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Comparative analyses of flavonoid content in Moringa oleifera and Moringa ovalifolia with the aid of UHPLC-qTOF-MS fingerprinting

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dc.contributor.author Makita, C
dc.contributor.author Chimuka, L
dc.contributor.author Steenkamp, Paul
dc.contributor.author Cukrowsk, E
dc.contributor.author Madala, E
dc.date.accessioned 2017-08-22T13:08:32Z
dc.date.available 2017-08-22T13:08:32Z
dc.date.issued 2016-07
dc.identifier.citation Makita, C., Chimuka, L., Steenkamp, P. et al. 2016. Comparative analyses of flavonoid content in Moringa oleifera and Moringa ovalifolia with the aid of UHPLC-qTOF-MS fingerprinting. South African Journal of Botany, vol. 105: 116-122. doi.org/10.1016/j.sajb.2015.12.007 en_US
dc.identifier.issn 0254-6299
dc.identifier.uri doi.org/10.1016/j.sajb.2015.12.007
dc.identifier.uri http://www.sciencedirect.com/science/article/pii/S0254629916002507
dc.identifier.uri http://hdl.handle.net/10204/9456
dc.description Copyright: 2016 SAAB. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, kindly consult the publisher's website. en_US
dc.description.abstract Moringa species are multipurpose plants with nutritional, medicinal and industrial benefits. The flavonoids content of Moringa oleifera and Moringa ovalifolia was studied using an Ultra high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UHPLC-ESI-qTOF-MS). The results revealed that the two species contain at least 17 flavonoids compounds between them. However, M. oleifera was found to contain the most flavonoids than M. ovalifolia which contained only three of the total flavonoids. Furthermore, all flavonoids in M. ovalifolia were shown to be glycosylated with only rutinoside. Based on the current findings, the two species seem to have a different composition of flavonoids, therefore suggesting an underlying variation at the genetic level for flavonoid biosynthesis. The difference in the flavonoids composition of the two species as seen from the results is mainly due to glycosylation capabilities, with M. oleifera being more superior in this case. Prior to this study, there has been no comprehensive investigation into the flavonoid content (or any phytochemical studies) of M. ovalifolia and its comparison to other Moringa species. Furthermore, vicenin-2 a molecule that has recently been linked to various medicinal properties has been identified in M. oleifera. Overall, M. oleifera (as compared to M. ovalifolia) is expected to exhibit wider pharmacological activities owing to its glycosylation complexity. en_US
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Worklist;18038
dc.subject Flavonoids en_US
dc.subject Glycosylation Moringaceae en_US
dc.subject Moringa oleifera en_US
dc.subject Moringa ovalifolia en_US
dc.subject UHPLC-QTOF-MS en_US
dc.title Comparative analyses of flavonoid content in Moringa oleifera and Moringa ovalifolia with the aid of UHPLC-qTOF-MS fingerprinting en_US
dc.type Article en_US


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