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dc.contributor.author Sakong, BM
dc.contributor.author Adenubi, OT
dc.contributor.author Pauw, E
dc.contributor.author Eloff, JN
dc.contributor.author Fouché, Gerda
dc.contributor.author Leboho, Tlabo
dc.contributor.author Wellington, Kevin W
dc.date.accessioned 2017-06-07T07:14:03Z
dc.date.available 2017-06-07T07:14:03Z
dc.date.issued 2016
dc.identifier.citation Fouche, G., Sakong, B.M., Adenubi, O.T. et al. 2016. Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus. Onderstepoort Journal of Veterinary Research, vol. 83(1): doi.org/10.4102/ojvr.v83i1.1164 en_US
dc.identifier.issn 0030-2465
dc.identifier.uri http://journals.co.za/content/opvet/83/1/EJC196363
dc.identifier.uri doi.org/10.4102/ojvr.v83i1.1164
dc.identifier.uri http://hdl.handle.net/10204/9194
dc.description Copyright: © 2016. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. en_US
dc.description.abstract The nematode, Haemonchus contortus, is responsible for major economic losses in the livestock industry. The management of parasites such as H. contortus has been through the use of synthetic parasiticides. This has resulted in the presence of residues in meat and milk, which affects food safety. The development of resistance to available anthelmintics coupled with their high cost has further complicated matters. This has led to the investigation of alternative methods to manage nematodes, including the use of plants and plant extracts as a potential source of novel anthelmintics. Acetone extracts were prepared from 15 South African plant species and their anthelmintic activity determined using the egg hatch assay (EHA). The leaf extract of Cleome gynandra had the best inhibitory activity (68% ± 3%) at a concentration of 2.5 mg/mL, followed by the stem extract of Maerua angolensis (65% ± 5%). The extracts had a relatively low toxicity on Vero cells determined by the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) cellular assay. en_US
dc.language.iso en en_US
dc.publisher AOSIS en_US
dc.relation.ispartofseries Worklist;18085
dc.subject Livestock production en_US
dc.subject Gastrointestinal parasites en_US
dc.subject Haemonchus contortus en_US
dc.subject South African plants en_US
dc.subject Livestock diseases en_US
dc.title Anthelmintic activity of acetone extracts from South African plants used on egg hatching of Haemonchus contortus en_US
dc.type Article en_US


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