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Show simple item record Karsten, AE Smit, Jacoba E 2012-03-22T14:44:10Z 2012-03-22T14:44:10Z 2012-03
dc.identifier.citation Karsten, AE and Smit, JE. 2012. Modelling and verification of melanin concentration on human skin type. Photochemistry and Photobiology, vol. 88(2), pp 469-474 en_US
dc.identifier.issn 0031-8655
dc.description Copyright: 2011 The American Society of Photobiology. This is the pre-print version of the work. The definitive version is published in Photochemistry and Photobiology, vol. 88(2), pp 469-474 en_US
dc.description.abstract Lasers are used in the minimalistic or noninvasive diagnosis and treatment of skin disorders. Less laser light reaches the deeper skin layers in dark skin types, due to its higher epidermal melanin concentration compared with lighter skin. Laser–tissue interaction modeling software can correct for this by adapting the dose applied to the skin. This necessitates an easy and reliable method to determine the skin’s type. Noninvasive measurement of the skin’s melanin content is the best method. However, access to samples of all skin types is often limited and skin-like phantoms are used instead. This study’s objective is to compare experimentally measured absorption features of liquid skin-like phantoms representing Skin Types I–VI with a realistic skin computational model component of ASAP®. Sample UV–VIS transmittance spectra were measured from 370 to 900 nm and compared with simulated results from ASAP® using the same optical parameters. Results indicated nonmonotonic absorption features towards shorter wavelengths, which may allow for more accurate ways of determining melanin concentration and expected absorption through the epidermal layer. This suggests possible use in representing optical characteristics of real skin. However, a more comprehensive model and phantoms are necessary to account for the effects of sun exposure. en_US
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.relation.ispartofseries Workflow;7606
dc.subject Sun exposure effects en_US
dc.subject Skin disorders en_US
dc.subject Laser skin treatment en_US
dc.subject Melanin concentration 1 en_US
dc.subject Laser lights en_US
dc.subject Melanin en_US
dc.subject Skin type en_US
dc.subject Computational modelling en_US
dc.subject Skin-like phantoms en_US
dc.subject Skin-like phantoms en_US
dc.subject Sun exposure en_US
dc.subject Melanin concentration en_US
dc.subject Absorption spectroscopy en_US
dc.subject Skin models en_US
dc.subject Liquid skin-like phantoms en_US
dc.subject Non-monotonic absorption features en_US
dc.title Modelling and verification of melanin concentration on human skin type en_US
dc.type Article en_US

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