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dc.contributor.author Stoev, SD
dc.contributor.author Dutton, MF
dc.contributor.author Njobeh, PB
dc.contributor.author Mosonik, JS
dc.contributor.author Steenkamp, PA
dc.date.accessioned 2010-08-23T13:09:56Z
dc.date.available 2010-08-23T13:09:56Z
dc.date.issued 2009
dc.identifier.citation Stoev, SD, Dutton, MF, Njobeh, PB. 2009. Mycotoxic nephropathy in Bulgarian pigs and chickens: complex aetiology and similarity to Balkan endemic nephropathy. Food Additives and Contaminants, Part A: Chemistry Analysis Control Exposure & Risk Assessment, Vol. 27(1), pp 72-88 en
dc.identifier.issn 1944-0049
dc.identifier.uri http://pdfserve.informaworld.com/929781_769431896_914865098.pdf
dc.identifier.uri http://hdl.handle.net/10204/4194
dc.description Copyright: 2009 Taylor & Francis. This is the authors pre-print version. The definitive version is published in the Journal of Food Additives and Contaminants, Part A: Chemistry Analysis Control Exposure & Risk Assessment, Vol. 27(1), pp 72-88 en
dc.description.abstract Spontaneous nephropathy in Bulgaria, which is observed frequently during meat inspection and which differs morphologically from the classical description of mycotoxic porcine/chicken nephropathy as made in Denmark, was found to have a multi-mycotoxic aetiology being mainly provoked by a combined effect of ochratoxin A, penicillic acid and fumonisin B1 in addition to a not-yet-known metabolite. Mean contamination levels of ochratoxin A were consecutively low (188.8 and 376.4 mgkg_1) in contrast to high contamination levels of fumonisin B1 (5564.1 and 3254.5 mgkg_1) and penicillic acid (838.6 and 904.9 mgkg_1) for 2006 and 2007, respectively. Some other mycotoxins with lower importance such as citrinin, penitrem A, etc., may also influence clinicopathological picture of this nephropathy. A heavy contamination with Gibberella fujikuroi var. moniliformis (Fusarium verticillioides) and Penicillium aurantiogriseum complex (mainly Penicillium polonicum) was observed in almost all examined feed samples coming from pig and chick farms with nephropathy problems from Bulgaria. In contrast, low contamination with Aspergillus ochraceus, Penicillium verrucosum and Penicillium citrinum was observed in the same feed samples and these species were isolated as very rare components of the mycobiota. en
dc.language.iso en en
dc.publisher Taylor & Francis en
dc.subject High-performance liquid chromatography en
dc.subject Mycology en
dc.subject Screening assays en
dc.subject Toxicology en
dc.subject Animal study en
dc.subject Fumonisins en
dc.subject Mycotoxins en
dc.subject Mycotoxins fungi en
dc.subject Mycotoxins ochratoxin A en
dc.subject Animal feed en
dc.title Mycotoxic nephropathy in Bulgarian pigs and chickens: complex aetiology and similarity to Balkan endemic nephropathy en
dc.type Article en


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