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dc.contributor.author Swai, H
dc.contributor.author Hillie, KT
dc.contributor.author Cingo, N
dc.contributor.author Kalombo, Lonji
dc.contributor.author Legodi, M
dc.contributor.author Semete, B
dc.date.accessioned 2008-12-10T12:24:12Z
dc.date.available 2008-12-10T12:24:12Z
dc.date.issued 2006-02
dc.identifier.citation Swai, H, Hillie, KT, Cingo, N, Kalombo, L, Legodi, M and Semete, B. 2006. Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD). CSIR Research and Innovation Conference: 1st CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 27-28 February 2006, pp1 en
dc.identifier.uri http://hdl.handle.net/10204/2697
dc.description CSIR Research and Innovation Conference: 1st CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 27-28 February 2006 en
dc.description.abstract In this study, isoniazid, one of the most potent anti-TB drugs, was successfully encapsulated in poly (D, L- lactide-co-glycolide) (PLG) and in alginate-chitosan polymeric systems using a double-emulsion method and a cation-induced gelation method, respectively. The formulations from both systems were spray dried to obtain free-flowing powder. For the PLG system, an increase in the temperature of the inlet drying air resulted in decreased particle size, as well as increased absolute zeta potential (surface charge) and encapsulation efficiency, whereas the alginate-chitosan system showed a decrease in the particle size, absolute zeta potential and encapsulation efficiency. The PLG system gave superior results, compared with the alginate-chitosan system, in terms of size, shape, absolute zeta potential and encapsulation efficiency en
dc.language.iso en en
dc.subject Anti-tuberculosis drugs en
dc.subject Nano encapsulation techniques en
dc.subject Nanoparticles en
dc.subject Poly (D, L-lactide-co-glycolide) en
dc.subject ATD
dc.subject PLG
dc.title Evaluation of nano encapsulation techniques in different polymeric system for the delivery of anti-tuberculosis drugs (ATD) en
dc.type Poster en


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