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dc.contributor.author Malabi, Rudzani
dc.contributor.author Manoto, Sello L
dc.contributor.author Ombinda-Lemboumba, Saturnin
dc.contributor.author Maaza, Malik
dc.contributor.author Mthunzi-Kufa, Patience
dc.date.accessioned 2019-08-15T08:42:41Z
dc.date.available 2019-08-15T08:42:41Z
dc.date.issued 2019-02
dc.identifier.citation Malabi, R., Manoto, S.L., Ombinda-Lemboumba, S., Maaza, M., and Mthunzi-Kufa, P. 2019. Detection of biological analytes using surface plasmon resonance as a biosensing technique for possible development of a point of care diagnostic tool. SPIE BiOS, 2019, Moscone Centre, San Francisco, California, United States, 2-7 February 2019. en_US
dc.identifier.uri https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10894/108940P/Detection-of-biological-analytes-using-surface-plasmon-resonance-as-a/10.1117/12.2509850.full?SSO=1
dc.identifier.uri https://doi.org/10.1117/12.2509850
dc.identifier.uri http://hdl.handle.net/10204/11091
dc.description Copyright: 2019 SPIE. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, kindly consult the publisher's website en_US
dc.description.abstract Surface Plasmon Resonance (SPR) is a very powerful optical sensing technique that detects bimolecular binding interactions and it has turned out to be a suitable platform for clinical analysis. In biological and chemical sensing applications, SPR is used to monitor molecular binding real-time and it also promotes epitope mapping for determining biomolecular structures such as the interactions of proteins, DNA and viruses. This sensing technique also provides sensitive, label free and real-time monitoring of reactions. In this study we have built, characterized and optimized the SPR system for biosensing applications. Spectroscopy and scanning electron microscopy were used to characterize the surface of the SPR biosensor chip functionalized with antibodies. The home-built SPR system was successful in detecting biological analytes thereby paving a way into designing a label-free point-of-care (POC) diagnostic tool. en_US
dc.language.iso en en_US
dc.publisher SPIE en_US
dc.relation.ispartofseries Worklist;22583
dc.subject Surface Plasmon Resonance en_US
dc.subject Metal thin film en_US
dc.subject Spectroscopy en_US
dc.subject Scanning Electron Microscope en_US
dc.subject Biosensors en_US
dc.title Detection of biological analytes using surface plasmon resonance as a biosensing technique for possible development of a point of care diagnostic tool en_US
dc.type Presentation en_US


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