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dc.contributor.author Aderibigbe, BA
dc.contributor.author Owonubi, SJ
dc.contributor.author Jayaramudu, J
dc.contributor.author Sadiku, ER
dc.contributor.author Ray, SS
dc.date.accessioned 2016-05-16T10:25:10Z
dc.date.available 2016-05-16T10:25:10Z
dc.date.issued 2015-10
dc.identifier.citation Aderibigbe, B.A. Owonubi, S.J. Jayaramudu, J. Sadiku, E.R. and Ray, S.S. 2015. Targeted drug delivery potential of hydrogel biocomposites containing partially and thermally reduced graphene oxide and natural polymers prepared via green process. Colloid And Polymer Science, 293, 409-420 en_US
dc.identifier.issn 0303-402X
dc.identifier.uri http://link.springer.com/article/10.1007%2Fs00396-014-3400-z#/page-1
dc.identifier.uri http://hdl.handle.net/10204/8551
dc.description Copyright: 2015 Springer. Due to copyright restrictions, the attached PDF file only contains the abstract of the full text item. For access to the full text item, please consult the publisher's website. The definitive version of the work is published in Colloid And Polymer Science, 293, 409-420 en_US
dc.description.abstract Hydrogel biocomposites containing a combination of partially and thermally reduced graphene oxide (rGO) and natural polymer were prepared by free radical polymerization. The effect of rGO and the natural polymer on the morphology of the hydrogel composites was studied. The 0.007 g of rGO was used for uniform dispersion within the hydrogel composite matrix. The swelling kinetic and swelling ratios of the composites were evaluated at pH 1.2 and 7.4. Drug release studies were performed at pH values of 1.2 and 7.4 simulating gastric juice and intestinal fluid pH, respectively. The hydrogel biocomposites were able to bypass the acidity of the simulated gastric juice without liberating substantial amounts of the loaded drug, suggesting that rGO containing hydrogels are potential targeted drug delivery systems. The hydrogel biocomposites were further characterized by Fourier transform spectroscopy, X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and differential scanning calorimetry. en_US
dc.language.iso en en_US
dc.publisher Springer en_US
dc.relation.ispartofseries Workflow;16352
dc.subject Graphene oxide en_US
dc.subject Targeted drug delivery en_US
dc.subject Hydrogels biocomposite en_US
dc.subject Drug release en_US
dc.title Targeted drug delivery potential of hydrogel biocomposites containing partially and thermally reduced graphene oxide and natural polymers prepared via green process en_US
dc.type Article en_US


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