A collaborative research programme between the Council for Scientific and Industrial Research (CSIR) in South Africa and the National Cancer Institute (NCI) in the USA aimed at the screening of plant extracts and identification of potentially new anti-cancer drug leads was initiated in 1999. Plant extracts that exhibited anti-cancer activity against a panel of three human cell lines (breast MCF7, renal TK10 and melanoma UACC62) at the CSIR were screened by the NCI against sixty human cancer cell lines organized into sub panels representing leukaemia, melanoma and cancer of the lung, colon, kidney, ovary and central nervous system.
Reference:
Khorombi, TE, et al. Investigation of South African plants for anti cancer properties. Pharmacologyonline, vol. 3, pp 494-500
Khorombi, T., Fouché, G., Kolesnikova, N., Maharaj, V., Nthambeleni, R., & Van der Merwe, M. R. (2006). Investigation of South African plants for anti cancer properties. http://hdl.handle.net/10204/826
Khorombi, TE, Gerda Fouché, NI Kolesnikova, VJ Maharaj, R Nthambeleni, and Martina R Van der Merwe "Investigation of South African plants for anti cancer properties." (2006) http://hdl.handle.net/10204/826
Khorombi T, Fouché G, Kolesnikova N, Maharaj V, Nthambeleni R, Van der Merwe MR. Investigation of South African plants for anti cancer properties. 2006; http://hdl.handle.net/10204/826.
