This presentation show how the formulation of multifunctional polymeric nanoparticles for encapsulation of ATD's with optimum physico-chemical properties has been achieved. Aptamers (against mannose receptors) can assist uptake of nanoparticles in TB
infected cells. The delivery of nanoparticles to site of infection can be achieved via active targeting without compromising properties of nanoparticles.
Reference:
Ramalapa, B. Aptamer and nanotechnology- based approaches for active targeted delivery of anti-tuberculosis drugs. CSIR biennial conference: Science Real & Relevant, Pretoria, 9-10 October 2012
Ramalapa, B. (2012). Aptamer and nanotechnology- based approaches for active targeted delivery of anti-tuberculosis drugs. http://hdl.handle.net/10204/6142
Ramalapa, B. "Aptamer and nanotechnology- based approaches for active targeted delivery of anti-tuberculosis drugs." (2012): http://hdl.handle.net/10204/6142
Ramalapa B, Aptamer and nanotechnology- based approaches for active targeted delivery of anti-tuberculosis drugs; 2012. http://hdl.handle.net/10204/6142 .