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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/5754

Title: Nucleic acid toolkit: Potential diagnosis and treatment of major infectious diseases endemic in developing countries
Authors: Millroy, L
Khati, M
Keywords: Nucleic acid toolkit
Infectious diseases
Developing countries diseases
Nucleic acid
Amino acid ligands
Aptamers
Aptamer research
Issue Date: Sep-2011
Publisher: Lambert Academic Publishing
Citation: Millroy, L and Khati, M. Nucleic acid toolkit: Potential diagnosis and treatment of major infectious diseases endemic in developing countries. Lambert Academic Publishing
Series/Report no.: Workflow;8559
Abstract: HIV/AIDS and TB are among the major infectious diseases and defining public health problems in developing countries. This book aims to give an overview of the epidemiology and also provide an understanding of the pathology of these diseases. It also provides insights into their current diagnostics and treatments and the future prospects. In particular, the book highlights the use of nucleic acid therapies and focuses on the use of aptamers as potential treatment and diagnostic tools for these diseases. Aptamers are synthetic nucleic acid or amino acid ligands that can be isolated to bind specific targets such as HIV and TB molecules with high affinity. Examples of the successes and failures of aptamers are drawn upon to provide a full understanding of the technology. The advantages over existing technologies are also discussed so as to illustrate the potential of aptamers in a number of applications. Finally, the shortfalls and future prospects of aptamer research are presented.
Description: Copyright: Lambert Academic Publishing
URI: http://hdl.handle.net/10204/5754
ISBN: 978-3-8454-7765-7
Appears in Collections:Human factors
General science, engineering & technology

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