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Show simple item record Henriques, R Griffiths, C Rego, EH Mhlanga, Musa 2011-12-14T10:34:57Z 2011-12-14T10:34:57Z 2011-05
dc.identifier.citation Henriques, R, Griffiths, C et al. 2011. PALM and STORM: unlocking live-cell super-resolution. Biopolymers, Vol 95(5), pp 322-331 en_US
dc.identifier.issn 0006-3525
dc.description Copyright: 2011 Wiley Blackwell. This is an ABSTRACT ONLY en_US
dc.description.abstract Live-cell fluorescence light microscopy has emerged as an important tool in the study of cellular biology. The development of fluorescent markers in parallel with super-resolution imaging systems has pushed light microscopy into the realm of molecular visualization at the nanometer scale. Resolutions previously only attained with electron microscopes are now within the grasp of light microscopes. However, until recently, live-cell imaging approaches have eluded super-resolution microscopy, hampering it from reaching its full potential for revealing the dynamic interactions in biology occurring at the single molecule level. Here we examine recent advances in the super-resolution imaging of living cells by reviewing recent breakthroughs in single molecule localization microscopy methods such as PALM and STORM to achieve this important goal. en_US
dc.language.iso en en_US
dc.publisher Wiley Blackwell en_US
dc.relation.ispartofseries Workflow request;6582
dc.subject Super-resolution en_US
dc.subject Microscopy methods en_US
dc.subject Single molecules en_US
dc.subject PALM en_US
dc.subject STORM en_US
dc.subject Live-cell imaging en_US
dc.subject Super-resolution microscopy en_US
dc.title PALM and STORM: unlocking live-cell super-resolution en_US
dc.type Article en_US

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