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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/5155

Title: Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C
Authors: Millroy, L
London, G
Veale, R
Weinberg, M
Khati, M
Keywords: Kinetics
Binding kinetics
Aptamers
HIV AIDS
HIV-1
Issue Date: Feb-2011
Publisher: Conference Poster
Citation: Millroy, L, London, G, Veale, R et al. 2011. Binding kinetics of aptamers to gp120 derived from HIV-1 subtype C. EMBO global exchange lecture course on HIV AIDS, Stellenbsoch, 30 January - 04 February 2011
Series/Report no.: Workflow request;5453
Abstract: Aptamers are artificial nucleic acid ligands that can be engineered to bind with high specificity to a macromolecule. Their binding specificity and small size allow for a range of therapeutic applications. One avenue of research is to develop aptamers with specific and strong affinity to the HIV-1 envelope glycoprotein gp120 and act as novel HIV-1 entry inhibitor drugs or as targeted drug delivery systems to HIV-1 infected cells. Prior to any downstream applications, novel gp120 aptamers need to be biophysically characterised with regards to their target binding characteristics.
Description: EMBO global exchange lecture course on HIV AIDS, Stellenbsoch, 30 January - 04 February 2011
URI: http://hdl.handle.net/10204/5155
Appears in Collections:General science, engineering & technology
Aptamer technology

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