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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/5083

Title: Optimization of electrospinning parameters for chitosan nanofibres
Authors: Jacobs, V
Patnaik, A
Anandjiwala, RD
Maaza, M
Keywords: Chitosan
Issue Date: Jun-2011
Publisher: Bentham Science Publishers
Citation: Jacobs, V, Patnaik, A, Anandjiwala, RD, et al. 2011. Optimization of electrospinning parameters for chitosan nanofibres. Current Nanoscience, Vol. 7(3), pp. 396-401
Series/Report no.: Workflow;6750
Abstract: Electrospinning of chitosan, a naturally occurring polysaccharide biopolymer, has been investigated. In this paper, the authors report the optimization of electrospinning process and solution parameters using factorial design approach to obtain uniform chitosan nanofibres. The parameters studied were electric field strength, ratio of solvents - trifluoroacetic acid (TFA)/ dichloromethane (DCM), concentration of chitosan in the spinning solution, their individual and interaction effects on the diameter of nanofibres. The selected parameters were varied at three levels (-1, 0 and +1) using Box and Behnken factorial design. The interaction effect between electric field strength (FS) and concentration of chitosan (CC) as well as that between the ratio of solvents - TFA/DCM (SC) and electric field strength played the most significant role, followed by the concentration of chitosan and lastly by the electric field strength in obtaining uniform nanofibres.
Description: Copyright: 2011 Bentham Science Publishers. This is the pre print version of the work. The definitive version is published in Current Nanoscience, Vol. 7(3), pp. 396-401
URI: http://www.ingentaconnect.com/content/ben/cnano/2011/00000007/00000003/art00016
ISSN: 1573-4137
Appears in Collections:Polymers and composites
National Centre for nano-structured materials
Fibres and textiles
Microbial expression systems
General science, engineering & technology

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