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Please use this identifier to cite or link to this item: http://hdl.handle.net/10204/4457

Title: Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments
Authors: Stark, T
Chakauya, E
Kabamba, A
Morris, L
Rybicki, E
Chikwamba, R
Keywords: Griffithsin
Anti-HIV lectin
Pharmaceuticals
Therapeutic molecules
Subcellular
CSIR Conference 2010
Issue Date: Aug-2010
Citation: Stark, T, Chakauya, E, Kabamba, A et al. 2010. Effect of expressing an anti-HIV lectin, Griffithsin, in different plant cellular compartments. CSIR 3rd Biennial Conference 2010. Science Real and Relevant. CSIR International Convention Centre, Pretoria, South Africa, 30 August – 01 September 2010, pp 18
Series/Report no.: Conference Presentation
Abstract: Sub-Saharan Africa remains the region most heavily affected by HIV, and the majority of new infections from heterosexual contact are in women. Griffithsin (GRFT), a lectin isolated from the red algae Griffithsia, has shown extreme potency against the Human Immunodeficiency Virus (HIV) in vitro in very low quantities. The molecular target of GRFT is the high mannose residues on the viral gp120 coat protein. Low cost production of GRFT and other anti-HIV drugs at minimal costs is crucial seeing that the high demand for anti-HIV drugs reside in poor developing countries.
Description: CSIR 3rd Biennial Conference. Science Real and Relevant, CSIR International Convention Centre, Pretoria, 30 August – 1 September 2010
URI: http://hdl.handle.net/10204/4457
Appears in Collections:CSIR Conference 2010
Microbial expression systems
Yeast expression systems
General science, engineering & technology

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