Supercritical Carbon-dioxide (CO2) is fast becoming an important commercial and industrial solvent of choice, largely due to its solvating efficiency and low environmental impact. In many instances, supercritical CO2 can replace the use of hazardous solvents as well as limit the use of precious water resources. Due to its “green” characteristics, much research has focused on using supercritical CO2 as solvent for the preparation of pharmaceutical and food products. At the Council for Scientific and Industrial Research (CSIR), we have already developed and patented an encapsulation method using supercritical CO2 and we are currently investigating the development of a novel transdermal drug delivery system using this technology to further strengthen our expertise in this field.
Reference:
Labuschagne, P.W. 2010. Supercritical CO2: a ‘green’ route for the encapsulation of drugs. CSIR 3rd Biennial Conference 2010. Science Real and Relevant. CSIR International Convention Centre, Pretoria, South Africa, 30 August – 01 September 2010, pp 1
Labuschagne, P. W. (2010). Supercritical CO2: a ‘green’ route for the encapsulation of drugs. CSIR. http://hdl.handle.net/10204/4284
Labuschagne, Philip W. "Supercritical CO2: a ‘green’ route for the encapsulation of drugs." (2010): http://hdl.handle.net/10204/4284
Labuschagne PW, Supercritical CO2: a ‘green’ route for the encapsulation of drugs; CSIR; 2010. http://hdl.handle.net/10204/4284 .
CSIR 3rd Biennial Conference 2010. Science Real and Relevant. CSIR International Convention Centre, Pretoria, South Africa, 30 August – 01 September 2010
