Spontaneous nephropathy in pigs seen in South Africa was found to have multi-mycotoxic etiology involving several mycotoxins such as ochratoxin A (OTA), penicillic acid (PA) and fumonisin B1 (FB1) in addition to a not yet identified mycotoxin. Contamination levels of OTA were comparatively low (67–75 µg/kg) in contrast to high contamination levels of FB1 (5,289–5,021 µg/kg) and PA (149–251 µg/kg). A heavy contamination with Gibberella fujikuroi var. moniliformis and Penicillium aurantiogriseum complex (mainly P. polonicum) was observed in the fed forages in contrast to the light contamination with Aspergillus ochraceus, P. verrucosum and P. citrinum. The pathomorphological picture of this nephropathy was found to differ from the classical description of mycotoxic porcine nephropathy as originally made in Scandinavia by the extensive vascular changes.
Reference:
Stoev, SD, Denev, S, Dutton, MF et al. 2009. Complex etiology and pathology of mycotoxic nephropathy in South African pigs. Mycotoxin Research, Vol. 26(1), pp 31-46
Stoev, S., Denev, S., Dutton, M., Njobeh, P., Mosonik, J., Steenkamp, P., & Petkov, I. (2009). Complex etiology and pathology of mycotoxic nephropathy in South African pigs. http://hdl.handle.net/10204/4193
Stoev, SD, S Denev, MF Dutton, PB Njobeh, JS Mosonik, PA Steenkamp, and I Petkov "Complex etiology and pathology of mycotoxic nephropathy in South African pigs." (2009) http://hdl.handle.net/10204/4193
Stoev S, Denev S, Dutton M, Njobeh P, Mosonik J, Steenkamp P, et al. Complex etiology and pathology of mycotoxic nephropathy in South African pigs. 2009; http://hdl.handle.net/10204/4193.
Copyright: 2009 Mycotoxin Research. This is the authors pre-print version. The definitive version is published in the Mycotoxin Research Journal, Vol. 26(1), pp 31-46
