It was found that the nitrile hydratases in microorganisms isolated from around the world had infra-species amino acid sequence differences, and this provided an explanation for the variability of nitrile substrate usage within the species. CSIR Biosciences Enzyme Technology supports the result - South African microbial diversity will include unique biocatalysts
Reference:
Brady, D, Molefe, M, Steenkamp, L.H. et al. 2006. Application of Biocatalysis in synthetic chemistry. CATSA, Mossel Bay, South Africa, 14-17 November, pp 52
Brady, D., Molefe, M., Steenkamp, L. H., Parkinson, C., Jordaan, J., Visser, D. F., ... Mathiba, K. (2006). Application of biocatalysis in synthetic chemistry. http://hdl.handle.net/10204/2857
Brady, D, M Molefe, Lucia H Steenkamp, C Parkinson, J Jordaan, Daniel F Visser, C Simpson, Varsha P Chhiba, and K Mathiba. "Application of biocatalysis in synthetic chemistry." (2006): http://hdl.handle.net/10204/2857
Brady D, Molefe M, Steenkamp LH, Parkinson C, Jordaan J, Visser DF, et al, Application of biocatalysis in synthetic chemistry; 2006. http://hdl.handle.net/10204/2857 .
