Council for Scientific and Industrial Research (CSIR) implemented an in-house anti-cancer screen aimed at testing several plant extracts. This was done in collaboration with the National Cancer Institute (NCI) in the USA and involved training of CSIR staff at the NCI. The CSIR screens extracts in vitro for anti-cancer activity against a panel of three human cancer cell lines namely, melanoma UACC-62, renal carcinoma TK-10, and breast adenocarcinoma MCF-7. Extracts of Phylica paniculata Willd. (Rhamnaceae) and Pergularia daemia (Forsk.) Chiov. (Asclepiadaceae) exhibited anti-cancer activity at the CSIR screen and were screened by the NCI against sixty human cancer cell lines organized into sub panels representing leukaemia, melanoma and cancer of the lung, colon, kidney, ovary and central nervous system
Reference:
Khorombi, TE, Fouche, G and Van Heerden, FR. 2006. Phytochemical investigation and the anti-cancer properties of pengularia daemia and phylica paniculata. Indigenous Plant Use Forum (IPUF) Conference, University of Botswana, pp 1
Khorombi, T., Fouché, G., & Van Heerden, F. (2006). Phytochemical investigation and the anti-cancer properties of pengularia daemia and phylica paniculata. http://hdl.handle.net/10204/2804
Khorombi, TE, Gerda Fouché, and FR Van Heerden. "Phytochemical investigation and the anti-cancer properties of pengularia daemia and phylica paniculata." (2006): http://hdl.handle.net/10204/2804
Khorombi T, Fouché G, Van Heerden F, Phytochemical investigation and the anti-cancer properties of pengularia daemia and phylica paniculata; 2006. http://hdl.handle.net/10204/2804 .
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