dc.contributor.author |
Rotherham, L
|
|
dc.contributor.author |
Gresh, L
|
|
dc.contributor.author |
Ngubane, N
|
|
dc.contributor.author |
Nhlapo, J
|
|
dc.contributor.author |
Khati, M
|
|
dc.date.accessioned |
2008-12-10T12:39:25Z |
|
dc.date.available |
2008-12-10T12:39:25Z |
|
dc.date.issued |
2008-11 |
|
dc.identifier.citation |
Rotherham, L, Gresh, L, Ngubane, N et al. 2008. New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers. Science real and relevant: 2nd CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 17 & 18 November 2008, pp 1 |
en |
dc.identifier.uri |
http://hdl.handle.net/10204/2700
|
|
dc.description |
Science Real and Relevant: 2nd CSIR Biennial Conference, CSIR International Convention Centre Pretoria, 17 & 18 November 2008 |
en |
dc.description.abstract |
The CSIR bioscientists are using aptamers to explore new strategies for diagnosis and mitigation of the virulence of TB. The scientists have expressed and purified His-tagged versions of TB secreted proteins ESAT-6 and CFP-10. These monomers were to form the heterodimer in vitro. The scientists test the ability of the apmaters to: 1) be used as TB diagnostics tools by detecting the presence of ESAT-6 and/or CFP-10 in blood or sputum samples; 2) inhibit the virulence of M. tuberculosis in vitro and in TB mouse models. |
en |
dc.language.iso |
en |
en |
dc.publisher |
CSIR |
en |
dc.subject |
Tuberculosis |
en |
dc.subject |
Aptamers |
en |
dc.title |
New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers |
en |
dc.type |
Conference Presentation |
en |
dc.identifier.apacitation |
Rotherham, L., Gresh, L., Ngubane, N., Nhlapo, J., & Khati, M. (2008). New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers. CSIR. http://hdl.handle.net/10204/2700 |
en_ZA |
dc.identifier.chicagocitation |
Rotherham, L, L Gresh, N Ngubane, J Nhlapo, and M Khati. "New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers." (2008): http://hdl.handle.net/10204/2700 |
en_ZA |
dc.identifier.vancouvercitation |
Rotherham L, Gresh L, Ngubane N, Nhlapo J, Khati M, New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers; CSIR; 2008. http://hdl.handle.net/10204/2700 . |
en_ZA |
dc.identifier.ris |
TY - Conference Presentation
AU - Rotherham, L
AU - Gresh, L
AU - Ngubane, N
AU - Nhlapo, J
AU - Khati, M
AB - The CSIR bioscientists are using aptamers to explore new strategies for diagnosis and mitigation of the virulence of TB. The scientists have expressed and purified His-tagged versions of TB secreted proteins ESAT-6 and CFP-10. These monomers were to form the heterodimer in vitro. The scientists test the ability of the apmaters to: 1) be used as TB diagnostics tools by detecting the presence of ESAT-6 and/or CFP-10 in blood or sputum samples; 2) inhibit the virulence of M. tuberculosis in vitro and in TB mouse models.
DA - 2008-11
DB - ResearchSpace
DP - CSIR
KW - Tuberculosis
KW - Aptamers
LK - https://researchspace.csir.co.za
PY - 2008
T1 - New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers
TI - New diagnostic and therapeutic tools for tuberculosis using anti-ESAT-6/CFP-10 aptamers
UR - http://hdl.handle.net/10204/2700
ER -
|
en_ZA |