Browsing Research Publications/Outputs by Author "Ncube, EN"

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Ambrafuran (AmbroxTM) synthesis from natural plant product precursors

Author: Ncube, EN ; Steenkamp, Lucia H ; Dubery, IA Date: Aug 2020 Ambergris, an excretion product of sperm whales, has been a valued agent in the formulation of perfumes. The composition of ambergris consists of two major components: 40–46% cholestanol type steroids and approximately 25–45% of a triterpenoid ... Read more
Analyses of chlorogenic acids and related cinnamic acid derivatives from Nicotiana tabacum tissues with the aid of UPLC-QTOF-MS/MS based on the in-source collision-induced dissociation method

Author: Ncube, EN ; Mhlongo, MI ; Piater, LA ; Steenkamp, PA ; Dubery, IA ; Madala, NE Date: Nov 2014 Chlorogenic acids (CGAs) are a class of phytochemicals that are formed as esters between different derivatives of cinnamic acid and quinic acid molecules. In plants, accumulation of these compounds has been linked to several physiological ... Read more
Chlorogenic acids biosynthesis in Centella asiatica cells is not stimulated by salicylic acid manipulation

Author: Ncube, EN ; Steenkamp, Paul A ; Madala, NE ; Dubery, IA Date: Jul 2016 Exogenous application of synthetic and natural elicitors of plant defence has been shown to result in mass production of secondary metabolites with nutraceuticals properties in cultured cells. In particular, salicylic acid (SA) treatment has ... Read more
Gas chromatographic profiling of the biocatalytic conversion of sclareol to ambradiol by Hyphozyma roseoniger

Author: Ncube, EN ; Mathiba, Kgama ; Steenkamp, Lucia H ; Dubery, IA Date: Oct 2021 Hyphozyma roseoniger is a filamentous yeast used for its biocatalytic ability to convert sclareol, a plant diterpenoid to ambradiol, an intermediate to ambrafuran, which is a sought-after fixative in the perfume industry. Metabolite profiling ... Read more
Stimulatory effects of acibenzolar-s-methyl on chlorogenic acids biosynthesis in Centella asiatica cells

Author: Ncube, EN ; Steenkamp, Paul A ; Madala, NE ; Dubery, IA Date: Sep 2016 Centella asiatica is a perrenial herb that grows in tropical regions with numerous medicinal properties mostly attributed to the presence of pentacyclic triterpenoids. Interestingly, this plant also possess a significant amount of ... Read more

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Browsing Research Publications/Outputs by Author "Ncube, EN"

Browsing Research Publications/Outputs by Author "Ncube, EN"

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