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Browsing Biosciences by Author "Zimmermann, S"

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  • Hata, Y; Raith, M; Ebrahimi, SN; Zimmermann, S; Mokoka, T; Naidoo, Dashnie; Fouché, Gerda; Maharaj, V; Kaiser, M; Brun, R; Hamburger, M (Georg Thieme Verlag, 2013-04)
    A library of 206 extracts from selected South African plants was screened in vitro against a panel of protozoan parasites, Plasmodium falciparum, Trypanosoma brucei rhodesiense, and Leishmania donovani. A CH(sub)2Cl(sub)2/MeOH ...
  • Mokoka, TA; Peter, Xolani K; Zimmermann, S; Hata, Y; Adams, M; Kaiser, M; Moodley, N; Maharaj, V; Koorbanally, Nicoli A; Hamburger, M; Brun, B; Fouché, Gerda (Georg Thieme Verlag, 2013-08)
    Two hundred and seven extracts were prepared from sixty plants from South Africa and screened for in vitro activity against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, and Plasmodium falciparum. ...
  • Hata, Y; Ebrahimi, SN; De Mieri, M; Zimmermann, S; Mokoka, T; Naidoo, Dashnie; Fouché, Gerda; Maharaj; Kaiser, M; Brun, R; Potterat, O; Hamburger, M (Elsevier, 2014-03)
    Human African trypanosomiasis is a neglected tropical disease in sub Saharan Africa that is fatal if left untreated. In a search for new natural products with antitrypanosomal activity, we recently identified abruquinones ...
  • Zimmermann, S; Fouché, Gerda; De Mieri, M; Yukiko, Y; Toyonobu, U; Nthambeleni, R; Parkinson, CJ; Van der Westhuyzen, Christiaan W; Kaiser, M; Hamburger, M; Adams, M (MDPI AG, Basel, Switzerland, 2014-03)
    Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis. To explore their ...

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