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Browsing by Author "Scholefield, Janine"

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The emerging molecular biology toolbox for the study of long noncoding RNA biology

Author: Fok, Ezio T ; Scholefield, Janine ; Fanucchi, Stephanie ; Mhlanga, Musa Date: Oct 2017 Long noncoding RNAs (lncRNAs) have been implicated in many biological processes. However, due to the unique nature of lncRNAs and the consequential difficulties associated with their characterization, there is a growing disparity between the ... Read more
Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti

Author: Scholefield, Janine ; Henriques, R ; Savulescu, AF ; Fontan, E ; Boucharlat, A ; Laplantine, E ; Smahi, A ; Israel, A ; Agou, F ; Mhlanga, Musa Date: Sep 2016 The NF- B pathway has critical roles in cancer, immunity and inflammatory responses. Understanding the mechanism(s) by which mutations in genes involved in the pathway cause disease has provided valuable insight into its regulation, yet many ... Read more
Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA

Author: Barichievy, Samantha ; Naidoo, Jerolen ; Boullé, M ; Scholefield, Janine ; Parihar, SP ; Coussens, AK ; Brombacher, F ; Sigal, A ; Mhlanga, Musa M Date: Aug 2018 An emerging realization of infectious disease is that pathogens can cause a high incidence of genetic instability within the host as a result of infection-induced DNA lesions. These often lead to classical hallmarks of cancer, one of which ... Read more

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Browsing by Author "Scholefield, Janine"

Browsing by Author "Scholefield, Janine"

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