Author:Chhiba, Varsha P; Bode, M; Mathiba, K; Brady, DDate:Jun 2014The use of enzymes for the enantioselective synthesis of single enantiomer ß-subsituted compounds is of interest, as this structural motif occurs commonly in compounds of pharmaceutical importance, such as adrenergic agents, antidiabetics, ...Read more
Author:Thuku, RN; Brady, D; Benedik, MJ; Sewell, BTDate:Mar 2009The nitrilases are enzymes that convert nitriles to the corresponding acid and ammonia. They are members of a superfamily, which includes amidases and occur in both prokaryotes and eukaryotes. The superfamily is characterized by having a ...Read more