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Browsing by Author "Naidoo, Jerolen"

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Lnc-ing inflammation to disease

Author: Magagula, L ; Gagliardi, M ; Naidoo, Jerolen ; Mhlanga, Musa Date: Aug 2017 Termed 'master gene regulators' long ncRNAs (lncRNAs) have emerged as the true vanguard of the 'noncoding revolution'. Functioning at a molecular level, in most if not all cellular processes, lncRNAs exert their effects systemically. Thus, ... Read more
Systems biology tools to understand the role of host miRNAs in infection: a closer look at HIV

Author: Naidoo, Jerolen ; Brackin, R ; Khutlang, Rethabile ; Savulescu, A ; Mhlanga, Musa Date: Jun 2014 The discovery of mammalian microRNAs (miRNAs) has greatly enhanced our appreciation for the complexity associated with the regulation of the mammalian transcriptional landscape. Endogenous miRNA pathways mediate the targeted and subtle ... Read more
Viral Apoptosis Evasion via the MAPK Pathway by Use of a Host Long Noncoding RNA

Author: Barichievy, Samantha ; Naidoo, Jerolen ; Boullé, M ; Scholefield, Janine ; Parihar, SP ; Coussens, AK ; Brombacher, F ; Sigal, A ; Mhlanga, Musa M Date: Aug 2018 An emerging realization of infectious disease is that pathogens can cause a high incidence of genetic instability within the host as a result of infection-induced DNA lesions. These often lead to classical hallmarks of cancer, one of which ... Read more

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Browsing by Author "Naidoo, Jerolen"

Browsing by Author "Naidoo, Jerolen"

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