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Browsing by Author "Mokoka, T"

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Antiprotozoal Isoflavan Quinones from Abrus precatorius ssp. africanus

Author: Hata, Y ; Raith, M ; Ebrahimi, SN ; Zimmermann, S ; Mokoka, T ; Naidoo, Dashnie ; Fouché, Gerda ; Maharaj, V ; Kaiser, M ; Brun, R ; Hamburger, M Date: Apr 2013 A library of 206 extracts from selected South African plants was screened in vitro against a panel of protozoan parasites, Plasmodium falciparum, Trypanosoma brucei rhodesiense, and Leishmania donovani. A CH(sub)2Cl(sub)2/MeOH (1:1) extract ... Read more
Antitrypanosomal isoflavan quinones from Abrus precatorius

Author: Hata, Y ; Ebrahimi, SN ; De Mieri, M ; Zimmermann, S ; Mokoka, T ; Naidoo, Dashnie ; Fouché, Gerda ; Maharaj ; Kaiser, M ; Brun, R ; Potterat, O ; Hamburger, M Date: Mar 2014 Human African trypanosomiasis is a neglected tropical disease in sub Saharan Africa that is fatal if left untreated. In a search for new natural products with antitrypanosomal activity, we recently identified abruquinones B and I from Abrus ... Read more
Solamargine, a bioactive steroidal alkaloid isolated from Solanum aculeastrum induces non-selective cytotoxicity and P-glycoprotein inhibition

Author: Burger, T ; Mokoka, T ; Fouché, Gerda ; Steenkamp, P ; Steenkamp, V ; Cordier, W Date: May 2018 Background: Solanum aculeastrum fruits are used by some cancer sufferers as a form of alternative treatment. Scientific literature is scarce concerning its anticancer activity, and thus the aim of the study was to assess the in vitro anticancer ... Read more

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Browsing by Author "Mokoka, T"

Browsing by Author "Mokoka, T"

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