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Evaluation of the photophysicochemical properties and photodynamic therapy activity of nanoconjugates of zinc phthalocyanine linked to glutathione capped Au and Au3Ag1 nanoparticles

Author: Oluwole, DA ; Manoto, Sello L ; Malabi, Rudzani ; Maphanga, Charles P ; Ombinda-Lemboumba, Saturnin ; Mthunzi-Kufa, Patience ; Nyokong, T Date: Mar 2018 We report on the synthesis of glutathione capped gold (AuNPs–GSH) and gold–silver (Au3Ag1NPs–GSH) nanoparticles and their covalent attachment to Zn monocarboxyphenoxy phthalocyanine (1) via amide bond formation. The photophysicochemical ... Read more
Investigation of South African plants for anti cancer properties

Author: Khorombi, TE ; Fouché, Gerda ; Kolesnikova, NI ; Maharaj, VJ ; Nthambeleni, R ; Van der Merwe, Martina R Date: 2006 A collaborative research programme between the Council for Scientific and Industrial Research (CSIR) in South Africa and the National Cancer Institute (NCI) in the USA aimed at the screening of plant extracts and identification of potentially ... Read more
Photodynamic effect of aluminium and zinc tetrasulfophthalocyanines on melanoma cancer cells

Author: Maduray, K ; Karsten, A ; Odhav, B ; Nyokong, T Date: Jun 2010 Aluminium and zinc tetrasulfophthalocyanines were activated with a 672nm wavelength laser to investigate the photodynamic effects on melanoma cancer, dermal fibroblast and epidermal keratinocyte cells. Aluminium tetrasulfophthalocyanine was ... Read more
Photodynamic therapy effect of aluminum and zinc tetrasulfophthalocyanines on melanoma cancer cells

Author: Maduray, K ; Karsten, A ; Odhav, B ; Nyokong, T Date: Jun 2010 Photodynamic therapy (PDT) represents a novel treatment that uses a photosensitizer (PS), light source (laser) of an appropriate wavelength and oxygen to induce cell death in cancer cells. The aim of this study was to investigate the photodynamic ... Read more
Potential solar UVR exposure health risks in South Africa

Author: Wright, CY Date: Sep 2010 The detrimental effects of excess personal solar ultraviolet radiation (UVR) exposure include wrinkles, immunosuppression and skin cancer. Approximately 1 000 South Africans die each year from melanoma skin cancer and 30% of all histologica ... Read more

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Browsing by Subject "Melanoma"

Browsing by Subject "Melanoma"

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