Author:Pillay, P; Maharaj, VJ; Clarkson, C; Chibale, KDate:Jan 2007Malaria is the leading cause of death and disease worldwide. The evolution and spread of drug-resistant forms of the causative agent Plasmodium falciparum and the limited number of chemotherapeutic agents available to treat and control the ...Read more
Author:Brown, B; Horak, M; Wadiwala, EDate:Nov 2008The production of essential oils and medicinal plant products by communities with access to arable land represents a promising new sector in the agroprocessing industry. The Enterprise Creation for Development (ECD) unit of the CSIR transfers ...Read more
Author:Adewusi, EA; Fouché, Gerda; Steenkamp, VDate:2013Amyloid-beta peptide (Aß) is implicated in the pathogenesis of Alzheimer’s disease (AD), a neurodegenerative disorder. This study was designed to determine the effect of four medicinal plants used to treat neurodegenerative diseases on ...Read more
Author:Faleschini, T; Fouché, Gerda; Harding, N; Myer, M; Dewar, JDate:01 Sep 2010Plants constitute the basic food chain and provide the most valuable source of natural nutrients; in addition, constituents of medicinal importance are also present in plants. For drug discovery and other purposes, we must characterise the ...Read more
Author:Fouché, Gerda; Cragg, GM; Pillay, P; Kolesnikova, NI; Maharaj, VJ; Senabe, JVDate:Oct 2008A total of 7500 plant extracts were screened for in vitro anticancer activity against a panel of three human cell lines (breast MCF7, renal TK10 and melanoma UACC62). Extracts were classified into four categories based on their total growth ...Read more
Author:Ndlovu, G; Fouché, Gerda; Tselanyane, MDate:Sep 2013Aging is an inevitable process for all living organisms that increases reactive oxygen species leading to the dysregulatian of extracellular and intracellular homeostasis, ultimately resulting in the skin not functioning optimally. The level ...Read more
Author:Seile, BP; Bareetseng, Andries S; Koitsiwe, MT; Aremu, AODate:Mar 2022Harvesting of medicinal plants in the wild has an impact on sustainability of medicinal plants, which leads to the need for intervention in terms of conservation strategies. Siphonochilus aethiopicus, commonly known as African ginger or wild ...Read more
Author:Pillay, P; Maharaj, VJ; Smith, PJDate:Oct 2008Based on the historical success of natural products as antimalarial drugs and the urgent need for new antimalarials, a number of South African medicinal plants have been evaluated for their antimalarial properties. This paper reviews the major ...Read more
Author:Adewusi, EA; Moodley, N; Steenkamp, VDate:Dec 2010Alzheimer’s disease (AD), a common neurodegenerative disease, is characterized by low levels in the brain of the neurotransmitter, acetylcholine (ACh). Clinical treatment of this disease is palliative and relies mostly on enhancing cholinergic ...Read more
Author:Fouché, Gerda; Van Rooyen, S; Faleschini, TDate:Feb 2013Asthma is a chronic inflammatory disease of the lungs, characterized by increased sensitivity to bronchoconstriction associated with infiltration of immune cells and mucus hyper secretion. In South Africa, the indigenous plant Siphonochilus ...Read more