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Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors

Author: Bode, ML ; Gravestock, D ; Moleele, SS ; Van der Westhuyzen, Christiaan W ; Pelly, SC ; Steenkamp, PA ; Hoppe, HC ; Khan, T ; Nkabinde, LA Date: Jun 2011 During random screening of a small in-house library of compounds, certain substituted imidazo[1,2-a]pyridines were found to be weak allosteric inhibitors of HIV-1 reverse transcriptase (RT). A library of these compounds was prepared using the ... Read more

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Browsing by Subject "Medicinal chemistry"

Browsing by Subject "Medicinal chemistry"

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