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Browsing by Subject "HIV-1 gp120"

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HIV-1 subtype C primary isolates exhibit high sensitivity to an anti-gp120 RNA aptamer

Author: Mufhandu, Hazel T ; Alexandre, Kabamba B ; Gray, ES ; Morris, L ; Khati, M Date: Sep 2012 Globally, HIV-1 subtype C is the most prevalent subtype, yet most antiretroviral drugs are developed against subtype B. UCLA1 RNA aptamer, which we previously showed neutralizes HIV-1 subtype C Env-pseudotyped viruses was examined for ... Read more
The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4+ cells

Author: Alexandre, Kabamba B ; Gray, ES ; Mufhandu, Hazel T ; McMahon, JB ; Chakauya, E ; O'Keefe, BR ; Chikwamba, Rachel K ; Morris, L Date: Feb 2012 It is generally believed that during the sexual transmission of HIV-1, the glycan-specific DC-SIGN receptor binds the virus and mediates its transfer to CD4(+) cells. The lectins griffithsin (GRFT), cyanovirin-N (CV-N) and scytovirin (SVN) ... Read more

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Browsing by Subject "HIV-1 gp120"

Browsing by Subject "HIV-1 gp120"

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