Author:Wellington, Kevin W; Steenkamp, P; Brady, DDate:Feb 2010Nuclear diamination of p-hydrobenzoquinones with aromatic and aliphatic primary amines was catalyzed by a immobilised commercial laccase, Denilite II Base, from Novozymes. The amine and the p-hydrobenzoquinone was reacted under mild conditions ...Read more
Author:Timothy, A; Akande, Amos A; Odoh, CK; Philip, M; Fidelis, TT; Amos, PI; Banjoko, OODate:Apr 2021Tremendous efforts in developing sustainable processes for integrated production of value-added products/chemicals and fuels in biorefineries increase through delicate designs towards sustainability. This review focuses on the synthesis of ...Read more
Author:Brady, D; Dube, N; Petersen, RLDate:Sep 2006The application of highly substrate-specific catalysts, such as biocatalysts, can reduce the number of synthetic steps required to generate organic compounds. A wide range of bacteria and yeast cultures were enriched on nitriles as the sole ...Read more
Author:Brady, D; Dube, N; Petersen, RDate:28 Feb 2006Nitrile substrate profiles were determined for a wide range of microorganisms. Isolated bacteria and yeast were enriched on nitriles as the sole nitrogen source. Aliphatic and aromatic nitriles were investigated, as well as structurally related ...Read more
Author:Makgwane, Peter R; Ray, SSDate:Oct 2013The development of green catalytic methods for chemical synthesis and energy generation based on nanocoated catalyst microfluidic systems is a growing area of innovative research. The interface between heterogeneous catalysis and microchannel ...Read more
Author:Wellington, Kevin W; Kolesnikova, NIDate:May 2012Nuclear monoamination of a 1,4-naphthohydroquinone with primary aromatic amines was catalysed by the commercial laccase, Novozym 51003, from Novozymes to afford aminonaphthoquinones. The synthesis was accomplished by reacting a mixture of the ...Read more
Author:Wellington, Kevin W; Govindjee, Varsha P; Steenkamp, PaulDate:Dec 2018A commercial laccase, Suberase from Novozymes, catalyses the synthesis of triaminated cyclohexa-2,4-dienones and a methylbenzene-1,2-diol derivative. The primary amine (analine) and the catechol was reacted under mild conditions (40C) in a ...Read more
Author:Wellington, Kevin W; Gordon, GER; Ndlovu, LA; Steenkamp, PDate:Jun 2013Oxidative C-S and C-C bond formation with aryl and alkyl thiols was catalyzed under mild conditions in a reaction vessel open to air at pH 4.5 in the presence of a commercial laccase (Novozym 51003 or Suberase) and a cosolvent (DMF) to afford ...Read more
Author:Mashweu, AR; Bode, ML; Brady, D; Chhiba, Varsha PDate:2020The aromatic substrate profile of the cobalt nitrile hydratase from Rhodococcus rhodochrous ATCC BAA 870 was evaluated against a wide range of nitrile containing compounds (>60). To determine the substrate limits of this enzyme, compounds ...Read more