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Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screens

Author: Meliopoulos, VA ; Andersen, LE ; Birrer, KF ; Simpson, KJ ; Lowenthal, JW ; Bean, AGD ; Stambas, J ; Stewart, CR ; Tompkins, SM ; Van Beusechem, VW ; Fraser, I ; Mhlanga, Musa ; Barichievy, S ; Smith, Q ; Leake, D ; Karpilow, J ; Buck, A ; Jona, G ; Tripp, RA Date: Jan 2012 Influenza virus encodes only 11 viral proteins but replicates in a broad range of avian and mammalian species by exploiting host cell functions. Genome-wide RNA interference (RNAi) has proven to be a powerful tool for identifying the host ... Read more

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Browsing by Subject "Genome"

Browsing by Subject "Genome"

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