Author:O'Kennedy, Maretha M; Grootboom, A; Shewry, PRDate:Nov 2006This review highlights recombinant DNA technology as a powerful tool to enhance the gene pools of sorghum and pearl millet crops regarded as jewels of Africa. Although important advances in the improvement of these species have been made by ...Read more
Author:Barros, EDate:May 2010In the early stages of production and commercialization of foods derived from genetically engineered (GE) plants, international consensus was reached on the principles of food safety evaluation. The concept of substantial equivalence became ...Read more
Author:Singh, Advaita A; Pillay, Priyen; Kwezi, Lusisizwe; Tsekoa, Tsepo LDate:Dec 2021Despite a reduction in global HIV prevalence the development of a pipeline of new therapeutics or pre-exposure prophylaxis to control the HIV/AIDS epidemic are of high priority. Antibody-based therapies offer several advantages and have been ...Read more
Author:Chakauya, E; Chikwamba, Rachel K; Rybick, EPDate:Aug 2006This article provides a background to biopharming, highlighting basic considerations for risk assessment and regulation in developing countries, with an emphasis on plant-based vaccines production in South Africa.Read more
Author:Mehlo, L; Grootboom, M; O'Kennedy, Maretha M; Okole, BDate:Feb 2006The goal of this project is to develop transgenic sorghum varieties that will deliver essential amino acids (lysine, threonine and tryptophan), vitamins A and E, iron and zinc - all of which are deficient in sorghum - to African populations ...Read more
Author:O'Kennedy, Maretha M; Burger, JT; Watson, TGDate:Apr 1998Focuses on the transformation of the embryogenic type II callus, initiated from cultured immature zygotic embryos of the maize line Hi-II, by microprojectile bombardment using a particle inflow gun. Use of the plasmid pAHC25; Tissue culture ...Read more
Author:Chakauya, E; Coxon, KM; Wei, M; MacDonald, MV; Barsby, T; Abell, C; Smith, AGDate:Nov 2008Pantothenate (vitamin B5) is the precursor of the 4'-phosphopantetheine moiety of coenzyme A and acyl-carrier protein. It is made by plants and microorganisms de novo, but is a dietary requirement for animals. The pantothenate biosynthetic ...Read more
Author:Girgi, M; O'Kennedy, Maretha M; Morgenstern, A; Mayer, G; Lorz, H; Oldach, KHDate:2002Four different pearl millet breeding lines were transformed and led to the regeneration of fertile transgenic plants. Scutellar tissue was bombarded with two plasmids containing the bar selectable marker and the beta-glucuronidase reporter ...Read more