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Characterization and in vitro release kinetics of antimalarials from whey protein-based hydrogel biocomposites

Author: Owonubi, SJ ; Aderibigbe, BA ; Mukwevho, E ; Sadiku, ER ; Ray, Suprakas S Date: Mar 2018 In this research, hydrogel biocomposites were prepared from whey protein isolate (WPI), reduced graphene oxide (rGO), and synthetic polymers in varied ratios. Their physicochemical properties were evaluated by FTIR, SEM, TGA, AFM, and TEM. ... Read more
Preliminary formulation and characterization of solid lipid nanoparticles containing chloroquine and a P-glycoprotein inhibitor: Influences of lipid-surfactant ratios

Author: Nzekwe, IT ; Azodo, VI ; Agubata, CO ; Naicker, B ; Okore, V ; Esimone, CO Date: Feb 2015 Chloroquine, a once useful therapy, currently faces problems of plasmodial resistance mediated through a number of mechanisms, such as P-glycoprotein (P-gp) mediated drug efflux, which makes attainment of adequate drug levels impossible. In ... Read more

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Browsing by Subject "Chloroquine"

Browsing by Subject "Chloroquine"

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