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A high-content subtractive screen for selecting small molecules affecting internalization of GPCRs

Author: Kwon, Y-J ; Lee, W ; Genovesio, A ; Emans, N Date: Mar 2012 G-protein–coupled receptors (GPCRs) are pivotal in cellular responses to the environment and are common drug targets. Identification of selective small molecules acting on single GPCRs is complicated by the shared machinery coupling signal ... Read more

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Browsing by Subject "Chemical biology"

Browsing by Subject "Chemical biology"

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