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Browsing by Author "Balogun, Mohammed O"

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Chemical modification of sugarcane bagasse with chitosan for the removal of phosphates in aqueous solution

Author: Manyatshe, Alusani ; Balogun, Mohammed O ; Nkambule, TTI ; Cele, Zamani ED ; Msagati, TAM Date: Nov 2020 Sugarcane bagasse is the major solid waste product of the sugarcane industry. As a plant-derived biomass, it is an attractive environmentally friendly alternative to petroleum-based materials. Being a non-food agriculture product, its use as ... Read more
CO2-assisted production of polyethylene glycol / lauric acid microparticles for extended release of Citrus aurantifolia essential oil

Author: Akolade, Jubril O ; Olubukola Nasir-Naeem, K ; Swanepoel, Andri ; Yusuf, AA ; Balogun, Mohammed O ; Labuschagne, Philip W Date: May 2020 Applications of essential oils as chemotherapeutics are limited because these aromatic oils are generally volatile, insoluble in aqueous media and easily degraded to non-active constituents when subjected to thermal-oxidative processes. The ... Read more
Fluorinated quaternary chitosan derivatives: Synthesis, characterization, antibacterial activity, and killing kinetics

Author: Cele, Zamani ED ; Somboro, AM ; Amoako, DG ; Ndlandla, Lindokuhle F ; Balogun, Mohammed O Date: Nov 2020 Chitosan has become an established platform biopolymer with applications in biomedical engineering, nanomedicine, and the development of new materials with improved solubility, antimicrobial activity, and low toxicity. In this study, a series ... Read more
Microencapsulation of eucalyptol in polyethylene glycol and polycaprolactone using particles from gas-saturated solutions

Author: Akolade, Jubril O ; Balogun, Mohammed O ; Swanepoel, Andri ; Ibrahim, RB ; Yusuf, AA ; Labuschagne, Philip W Date: Oct 2019 Eucalyptol is the natural cyclic ether which constitutes the bulk of terpenoids found in essential oils of Eucalyptus spp. and is used in aromatherapy for treatment of migraine, sinusitis, asthma and stress. It acts by inhibiting arachidonic ... Read more
Nanomedicines for malaria chemotherapy: Encapsulation vs. polymer therapeutics

Author: Mvango, Sindisiwe ; Matshe, William MR ; Balogun, AO ; Pilcher, LA ; Balogun, Mohammed O Date: Dec 2018 Malaria is one of the oldest infectious diseases that afflict humans and its history extends back for millennia. It was once prevalent throughout the globe but today it is mainly endemic to tropical regions like sub-Saharan Africa and South-east ... Read more
Performance evaluation of polypyrrole-montmorillonite clay composite as a re-usable adsorbent for Cr(VII) remediation

Author: Mdlalose, Lindani M ; Balogun, Mohammed O ; Setshedi, Katlego Z ; Chimuka, L ; Chetty, Avashnee Date: Aug 2020 A flexible composite adsorbent combination of polypyrrole and montmorillonite clay (PPy-MMT) has been prepared by in situ oxidative polymerization method. This well-achieved adsorbent has amphoteric characteristics and has been explored in ... Read more
Physico-chemical characterization of polyethylene glycol-conjugated betulinic acid

Author: Mvango, Sindisiwe ; Mthimkhulu, N ; Fru, PA ; Pilcher, LA ; Balogun, Mohammed O Date: Nov 2020 Betulinic acid (BA) is a naturally occurring plant pentacyclic triterpenoid with activity against cancer and infectious diseases like malaria and AIDS. Its pharmacological activity is limited by low aqueous solubility and bioavailability. ... Read more
Physicochemical and in vitro cytotoxicity evaluation of polymeric drugs for combination cancer therapy

Author: Aderibigbe, BA ; Naki, T ; Steenkamp, V ; Nwamadi, M ; Ray, Suprakas S ; Balogun, Mohammed O ; Matshe, William MR Date: Sep 2019 Platinum-based drugs are potent anticancer drugs and are effective for the treatment of various cancers. However, they are limited pharmacologically due to toxic side effects, drug resistance and poor water solubility. In order to overcome ... Read more
Polyamidoamine drug conjugates containing metal-based anticancer compounds

Author: Aderibigbe, BA ; Mugogodi, A ; Nwamadi, M ; Ray, Suprakas S ; Steenkamp, V ; Balogun, Mohammed O ; Matshe, William MR Date: Sep 2019 Polyamidoamine drug conjugates containing ferrocene and platinum analogues were prepared in this study. Fourier transform infrared spectra confirmed the successful isolation of the conjugates with signals at 3300 cm-1 for amide N–H stretch ... Read more
Polymer-drug conjugates containing antimalarial drugs and antibiotics

Author: Alven, S ; Aderibigbe, BA ; Balogun, Mohammed O ; Matshe, William MR ; Ray, Suprakas S Date: Oct 2019 Most of the currently used antimalarial drugs suffer from drug resistance, poor bioavailability and biodegradability, drug toxicity and poor water solubility. To overcome some of the aforementioned limitations, combination therapy involving ... Read more
Synthesis of a novel amphiphilic nano-chitosan material

Author: Matshe, William MR ; Tshweu, Lesego L ; Balogun, Mohammed O Date: Oct 2018 Chitosan (CS) is a semi-synthetic polysaccharide derived from the most abundant naturally occurring polymer, chitin. It has found applications in fields as diverse as health, cosmetics, agriculture, environmental remediation etc. While ... Read more
Synthesis, characterization and in vitro analysis of polymer-based conjugaes containing dihydrofolate reductase inhibitors

Author: Aderibigbe, AB ; Mhlatika, Z ; Nwamadi, M ; Balogun, Mohammed O ; Matshe, William MR Date: Feb 2019 Malaria is an acute disease that is caused by the protozoanPlasmodiumparasites. Drug resistance is the majorproblem that is hindering the control of this disease. In order to overcome drug resistance to commonly usedantimalarials, nanocarriers ... Read more
Synthesis, characterization and in vitro analysis of polymer-based conjugates containing dihydrofolate reductase inhibitors

Author: Aderibigbe, BA ; Mhlwatika, Z ; Nwamadi, M ; Balogun, Mohammed O ; Matshe, William MR Date: Apr 2019 Malaria is an acute disease that is caused by the protozoan Plasmodium parasites. Drug resistance is the major problem that is hindering the control of this disease. In order to overcome drug resistance to commonly used antimalarials, ... Read more
Synthesis, characterization and optimization of poly(p-phenylenediamine)-based organoclay composite for Cr(VI) remediation

Author: Mdlalose, L ; Balogun, Mohammed O ; Setshedi, K ; Tukulula, M ; Chimuka, L ; Chetty, A Date: Apr 2017 The contamination of the water supply with high levels of heavy metals from various human and industrial activities continues to present a major environmental problem. Heavy metals such as hexavalent chromium (Cr(VI)) are of particular concern ... Read more
Synthesis, physicochemical characterization, toxicity and efficacy of a PEG conjugate and a hybrid PEG conjugate nanoparticle formulation of the antibiotic moxifloxacin

Author: Tshweu, Lesego L ; Shemis, MA ; Abdelghany, C ; Gouda, A ; Pilcher, LA ; Sibuyi, NRS ; Meyer, M ; Dube, A ; Balogun, Mohammed O Date: May 2020 Antibiotic resistance is increasing at such an alarming rate that it is now one of the greatest global health challenges. Undesirable toxic side-effects of the drugs lead to high rates of non-completion of treatment regimens which in turn ... Read more

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