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Evaluation of the probable synergistic toxicity of selected potentiated antiretroviral and antibiotics on some aquatic biomarker organisms

Author: Omotola, EO ; Genthe, B ; Ndlela, Luyanda L ; Olatunji, OS Date: Nov 2023 Environmental effects of active pharmaceutical compounds (APCs) in the environment are not well characterized, hence the need for comprehensive evaluation. This study employed three bioassays using three organisms, namely, Allium cepa, Daphnia ... Read more
Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors

Author: Bode, ML ; Gravestock, D ; Moleele, SS ; Van der Westhuyzen, Christiaan W ; Pelly, SC ; Steenkamp, PA ; Hoppe, HC ; Khan, T ; Nkabinde, LA Date: Jun 2011 During random screening of a small in-house library of compounds, certain substituted imidazo[1,2-a]pyridines were found to be weak allosteric inhibitors of HIV-1 reverse transcriptase (RT). A library of these compounds was prepared using the ... Read more

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Browsing by Subject "Antiretroviral"

Browsing by Subject "Antiretroviral"

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