Author:Pillay, P; Maharaj, V; Crouch, N; Smith, P; Lategan, C; Vleggaar, RDate:Feb 2006With the emergence and spread of drug- resistant parasites, there is a need for new chemically diverse, effective antimalarial drugs. A national multidisciplinary consortium was established to validate scientifically South African medicinal ...Read more
Author:Aderibigbe, BA; Sadiku, ER; Jayaramudu, J; Ray, SSDate:Oct 2014The potential of gum acacia containing hydrogels as controlled dual-drug delivery systems for antiprotozoal agents was investigated. 4-Aminoquinoline analog and curcumin were selected as model drugs because they exhibit antiprotozoal activity. ...Read more
Author:Setshedi, I; Peter, Xolani K; Fouché, Gerda; Myer, M; Dewar, JDate:01 Sep 2010The genus Sceletium is classified as part of the Family Mesembryanthemaceae and belongs to the sub-family Mesembryanthemoideae. Some of the names used when referring to this genus are ‘living skeletons’ or ‘skeleton plants’ (http://ujdigisp ...Read more
Author:Mvango, Sindisiwe; Matshe, William MR; Balogun, AO; Pilcher, LA; Balogun, Mohammed ODate:Dec 2018Malaria is one of the oldest infectious diseases that afflict humans and its history extends back for millennia. It was once prevalent throughout the globe but today it is mainly endemic to tropical regions like sub-Saharan Africa and South-east ...Read more
Author:Aderibigbe, BA; Ray, Suprakas SDate:Sep 2016Malaria is treated by combination of two drugs in order to overcome drug resistance. Antimalarials have been found to be more effective by combining them with low doses of anticancer drugs. Polymer-drug conjugates containing aminoquinoline ...Read more
Author:Aderibigbe, BA; Neuse, EW; Sadiku, ER; Shina Ray, S; Smith, PJDate:2014In this research, aminoquinoline compounds were synthesized, characterized and incorporated into water soluble polymers to form conjugates. The conjugates were characterized by X ray Diffraction (XRD), Thermal Gravimetric Analysis (TGA), ...Read more