Author:Wellington, Kevin W; Qwebani-Ogunleye, T; Kolesnikova, NI; Brady, D; De Koning, CBDate:Apr 2013A commercial laccase, Suberase® from Novozymes, was used to catalyse the synthesis of 5,6-dihydroxylated benzo[b]furans and catechol derivatives. The yields were, in some cases, similar to or better than that obtained by other enzymatic, ...Read more
Author:Aderibigbe, BA; Ray, Suprakas SDate:Sep 2016Malaria is treated by combination of two drugs in order to overcome drug resistance. Antimalarials have been found to be more effective by combining them with low doses of anticancer drugs. Polymer-drug conjugates containing aminoquinoline ...Read more
Author:Aderibigbe, BA; Sadiku, ER; Ray, SS; Mbianda, XY; Fotsing, MC; Agwuncha, SC; Owonubi, SJDate:Oct 2015Polyamidoamine conjugates of neridronic acid were synthesized by a one-pot aqueous phase Michael addition reaction of N, N0-methylenebisacrylamide with selected primary and secondary amines and neridronic acid. This reaction involved the use ...Read more
Author:Aderibigbe, BA; Sadiku, ER; Ray, SS; Mbianda, XY; Fotsing, MC; Jayaramudu, J; Owonubi, SJDate:2015Polyamidoamine conjugates containing curcumin and bisphosphonate were synthesized via a one-pot aqueous phase Michael addition reaction. In the design of the conjugate, bisphosphonate formed an integral part of the polymer carrier backbone. ...Read more