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Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore

Author: Pillay, P ; Vleggaar, R ; Maharaj, VJ ; Smith, PJ ; Lategan, CA ; Chouteau, F ; Chibale, K Date: Feb 2007 The dichloromethane extract of the leaves of Vernonia staehelinoides Harv. (Asteraceae) showed in vitro activity (IC50 ~3 µg/ml) against the chloroquine-sensitive (D10) and the chloroquine-resistant (K1) strains of Plasmodium falciparum. ... Read more

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Browsing by Subject "2(5H)-furanone"

Browsing by Subject "2(5H)-furanone"

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