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Rapid formation of 2-lithio-1-(triphenylmethyl)imidazole and substitution reactions in flow†

Author: Wang, S ; Panayides, Jenny-Lee ; Riley, D ; Tighe, CJ ; Hii, KK Date: Sep 2021 The functionalisation of imidazoles is a necessary step in the formation of many active pharmaceutical intermediates. Herein, we report a flow chemistry approach for the rapid and efficient formation of 2-lithio-1-(triphenylmethyl)imidazole ... Read more

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Browsing by Subject "Pharmaceutical intermediates"

Browsing by Subject "Pharmaceutical intermediates"

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