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UCLA1 aptamer inhibition of human immunodeficiency virus type 1 subtype C primary isolates in macrophages and selection of resistance

Author: Mufhandu, Hazel T ; Alexandre, Kabamba B ; Gray, ES ; Morris, L ; Khati, M Date: Sep 2016 We have previously shown that the aptamer, UCLA1, is able to inhibit HIV-1 replication in peripheral blood mononuclear cells (PBMCs) by binding to residues in gp120. In this study we examined whether UCLA1 was effective against HIV-1 subtype ... Read more

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Browsing by Subject "Monocyte-derived macrophages"

Browsing by Subject "Monocyte-derived macrophages"

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