Author:Pillay, P; Maharaj, VJ; Clarkson, C; Chibale, KDate:Jan 2007Malaria is the leading cause of death and disease worldwide. The evolution and spread of drug-resistant forms of the causative agent Plasmodium falciparum and the limited number of chemotherapeutic agents available to treat and control the ...Read more
Author:Steenkamp, PA; Harding, NM; Van Heerden, FR; Van Wyk, BEDate:Nov 2006An LC-MS screening method was developed to detect the presence of atractyloside (ATR), the toxic principle of a commonly used medicinal plant in South Africa, Callilepis laureola, in biological matrices such as body fluids and human viscera. ...Read more
Author:Fouché, Gerda; Cragg, GM; Pillay, P; Kolesnikova, NI; Maharaj, VJ; Senabe, JVDate:Oct 2008A total of 7500 plant extracts were screened for in vitro anticancer activity against a panel of three human cell lines (breast MCF7, renal TK10 and melanoma UACC62). Extracts were classified into four categories based on their total growth ...Read more