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Design, synthesis, and in vitro antituberculosis activity of 2(5H)-Furanone derivatives

Author: Ngwane, AH ; Panayides, Jenny-Lee ; Chouteau, F ; Macingwana, L ; Viljoen, A ; Baker, B ; Madikane, E ; De Kock, C ; Wiesner, L ; Chibale, K ; Parkinson, CJ ; Mmutlane, EM ; Van Helden, P ; Wiid, I Date: Jan 2016 A series of 2(5H)-furanone-based compounds were synthesized from commercially available mucohalic acids. From the first-generation compounds, three showed inhibitory activity (10 µg/mL) of at least 35% against Mycobacterium smegmatis mc(2) ... Read more

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Browsing by Subject "Antimycobacterial"

Browsing by Subject "Antimycobacterial"

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