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Browsing by Subject "Anti-HIV antibodies"

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Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications

Author: Singh, Advaita Acarya ; Pooe, O ; Kwezi, Lusisizwe ; Lotter-Stark, T ; Stoychev, Stoyan H ; Alexandra, Kabamba B ; Gerber, Isak B ; Bhiman, JN ; Vorster, J ; Pauly, M ; Zeitlin, L ; Whaley, K ; Mach, L ; Steinkellner, H ; Morris, L ; Tsekoa, Tsepo L ; Chikwamba, Rachel K Date: Apr 2020 Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention and treatment. These Abs carry a unique but crucial post-translational modification (PTM), ... Read more
A plant-biotechnology approach for producing highly potent anti-HIV antibodies for antiretroviral therapy consideration

Author: Singh, Advaita A ; Pillay, Priyen ; Kwezi, Lusisizwe ; Tsekoa, Tsepo L Date: Dec 2021 Despite a reduction in global HIV prevalence the development of a pipeline of new therapeutics or pre-exposure prophylaxis to control the HIV/AIDS epidemic are of high priority. Antibody-based therapies offer several advantages and have been ... Read more

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Browsing by Subject "Anti-HIV antibodies"

Browsing by Subject "Anti-HIV antibodies"

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