Author:Van van der Westhuizen, Johan C; Stander, A; Riley, DL; Panayides, Jenny-LeeDate:Mar 2022Alzheimer's disease is the most common neurodegenerative disease and currently poses a significant socioeconomic problem. This study describes the uses of computer-aided drug discovery techniques to identify novel inhibitors of acetylcholinesterase, ...Read more
Author:Thakur, A; Moyo, P; Van Der Westhuizen, Carl Johan; Yang, HO; Maharaj, VDate:Jul 2021Elevated levels of the amylo ß-proteins (Aß), particularly Aß42, are associated with a high risk of Alzheimer's disease (AD). The Aß proteins are produced from cellular processing of the amyloid precursor proteins (APPs). To identify natural ...Read more