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Imidazo[1,2-a]pyridines as NNRTIs

Author: Bode, ML ; Gravestock, D ; Moleele, S ; Van der Westhuyzen, Christiaan W ; Hoppe, H ; Khan, T ; Pelly, SC Date: Jan 2010 The enzyme reverse transcriptase (RT) is a validated target for the development of anti-HIV drugs. Drugs acting against RT may act at either the catalytic site (NRTIs) or the allosteric site (NNRTIs). During random screening of a small in-house ... Read more

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Browsing by Subject "Allosteric site"

Browsing by Subject "Allosteric site"

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