Author:Morris, EJ; Erasmus, C; O'Kennedy, Maretha MDate:Sep 2016Biopharmaceutical proteins and vaccines are traditionally produced in bacteria, eggs, yeast and animal cell cultures and are well established industries. More recently, these molecules are produced in plants and became known as biopharming. ...Read more
Author:Sepotokele, KM; O’Kennedy, Martha M; Hayes, MC; Wandrag, DBR; Smith, P; Abolnik, CDate:Oct 2023Infectious bronchitis (IB) Gammacoronavirus causes a highly contagious respiratory disease in chickens that is listed by the World Organisation for Animal Health (WOAH). Its high mutation ability has resulted in numerous variants against which ...Read morecbnd
Author:Singh, Advaita A; Pillay, Priyen; Tsekoa, Tsepo LDate:Nov 2021Since the demonstration of the first plant-produced proteins of medical interest, there has been significant growth and interest in the field of plant molecular farming, with plants now being considered a viable production platform for vaccines. ...Read more
Author:Meyers, A; Chakauya, E; Shepard, E; Tanzer, FL; Lynch, A; Williamson, A; Rybicki, EPDate:23 Jun 2008Human immunodeficiency virus type 1 (HIV-1) has infected more than 40 million people worldwide, mainly in sub-Saharan Africa. The high prevalence of HIV-1 subtype C in southern Africa necessitates the development of cheap, effective vaccines. ...Read more
Author:Chakauya, E; Chikwamba, Rachel K; Rybick, EPDate:Aug 2006This article provides a background to biopharming, highlighting basic considerations for risk assessment and regulation in developing countries, with an emphasis on plant-based vaccines production in South Africa.Read more