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Anti-mycobacterial peroxides: A new class of agents for development against tuberculosis

Author: Van der Westhuyzen, Christiaan W ; Haynes, J ; Panayides, Jenny-Lee ; Wiid, I ; Parkinson, C Date: 2020 Background: With few exceptions, existing tuberculosis drugs were developed many years ago and resistance profiles have emerged. This has created a need for new drugs with discrete modes of action. There is evidence that tuberculosis (like ... Read more
Effect of substituent structure on pyrimidine electrophilic substitution

Author: Van der Westhuyzen, Christiaan W ; Rousseau, AL ; Parkinson, CJ Date: 2007 In an investigation into the electrophilic nitrosation reactions of a series of 4,6-disubstituted pyrimidine derivatives, a subtle interplay between the electronic nature of the C-4 and C-6 substituents and reactivity was found where these ... Read more

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Browsing by Subject "Pyrimidine"

Browsing by Subject "Pyrimidine"

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