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Browsing by Subject "Pharmacophores"

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Antimalarial properties of South African medicinal plants

Author: Pillay, P ; Maharaj, VJ ; Clarkson, C ; Chibale, K Date: Jan 2007 Malaria is the leading cause of death and disease worldwide. The evolution and spread of drug-resistant forms of the causative agent Plasmodium falciparum and the limited number of chemotherapeutic agents available to treat and control the ... Read more
Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore

Author: Pillay, P ; Vleggaar, R ; Maharaj, VJ ; Smith, PJ ; Lategan, CA ; Chouteau, F ; Chibale, K Date: Feb 2007 The dichloromethane extract of the leaves of Vernonia staehelinoides Harv. (Asteraceae) showed in vitro activity (IC50 ~3 µg/ml) against the chloroquine-sensitive (D10) and the chloroquine-resistant (K1) strains of Plasmodium falciparum. ... Read more

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Browsing by Subject "Pharmacophores"

Browsing by Subject "Pharmacophores"

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